Fig 1: Angiotensin Converting Enzyme 2 (ACE2) concentration in Bronchoalveolar lavage fluid (BALF) samples. Lipopolysaccharide (LPS) instillation resulted in a significant increase in BALF ACE2 concentration (compared to the unstimulated contralateral side, p = 0.016) that could be mitigated by systemic application of dexamethasone (no significant difference). We present boxplots and whiskers (5–95% percentile). N = 24. * means statistically significant.
Fig 2: Changes in serum Ang-(1–7) and ACE2 levels 24 weeks after treatment with olmesartan (N = 36) or amlodipine (N = 35). ACE2 angiotensin-converting enzyme 2; Ang-(1–7), angiotensin-(1–7)
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